Author

S. Oscarson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:proteomics· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:C. elegans· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Organism:mouse· 2

Frequent Co-Authors

M. P. Wear· 3 shared A. Casadevall· 2 shared C. J. Crawford· 2 shared A. A. Casadevall· 1 shared A. A. Hargett· 1 shared A. Basle· 1 shared A. Butsyk· 1 shared A. Cartmell· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersImmunology

M. P. Wear

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Semi-synthetic glycoconjugate vaccine candidate against Cryptococcus neoformans

C. J. Crawford, L. Liporagi-Lopes, C. Coelho, S. R. Santos Junior, A. M. Nicola, M. P. Wear, S. Oscarson, A. Casadevall

This paper presents two semi-synthetic glycoconjugate vaccines targeting Cryptococcus neoformans GXM, showing immunogenicity and cross-reactivity in mice.

bioRxiv · Feb 2, 2024 · PreprintImmunology

The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: a combined NMR and MD study

A. A. Hargett, H. F. Azurmendi, C. J. Crawford, M. P. Wear, S. Oscarson, A. A. Casadevall, D. I. Freedberg

This study uses NMR and MD simulations to determine the structure of a synthetic C. neoformans polysaccharide, revealing its extended conformation and structural features recognized by protective antibodies.

bioRxiv · Sep 6, 2023 · PreprintBiochemistry

Helicobacter pylori attachment-blocking antibodies protect against duodenal ulcer disease

T. Boren, J. A. Bugaytsova, K. Moonens, A. Piddubnyi, A. Schmidt, J. O. Edlund, G. Lisiutin, K. Brannstrom, Y. A. Chernov, K. Thorell, I. Tkachenko, O. Sharova, I. Vikhrova, A. Butsyk, P. Shubin, , P. Aro

The paper shows that antibodies blocking H. pylori attachment reduce chronic inflammation and duodenal ulcer risk by mimicking BabA's binding to ABO glycans.

bioRxiv · May 24, 2023 · PreprintImmunology

Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE-2 in vitro

K. Khanna, W. Raymond, J. Jin, A. R. Charbit, I. Gitlin, M. Tang, A. D. Werts, E. G. Barrett, J. M. Cox, S. M. Birch, R. Martinelli, H. S. Sperber, S. Franz, S. Pillai, A. M. Healy, , J. V. Fahy

Thiol drugs inhibit SARS-CoV-2 infection in vitro and reduce lung injury in vivo, supporting their potential as COVID-19 treatments.

bioRxiv · Dec 8, 2020 · PreprintMicrobiology

A single bacterial sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium

A. S. Luis, C. Jin, G. Vasconcelos Pereira, R. W. P. Glowacki, S. Gugel, S. Singh, D. P. Byrne, N. A. Pudlo, J. A. London, A. Basle, M. Reihill, S. Oscarson, P. Eyers, M. Czjzek, G. Michel, , E. C. Martens

This study identifies a single sulfatase essential for colonic mucin O-glycan metabolism and intestinal colonization by Bacteroides thetaiotaomicron.

bioRxiv · Nov 20, 2020 · PreprintMicrobiology

Insight into glycosphingolipid crypticity: Crystal structure of the anti-tumor antibody 14F7 and recognition of NeuGc GM3 ganglioside

K. Bjerregaard-Andersen, H. Johannesen, F. Abraha, A. Sakanovic, D. Grosser, U. Coskun, G. Anderluh, S. Oscarson, E. Moreno, M. Grzybek, U. Krengel

This paper presents the crystal structure of the 14F7 antibody bound to NeuGc GM3 and shows how membrane composition and curvature influence its binding.

bioRxiv · Sep 18, 2020Biochemistry

Exploring Cryptococcus neoformans capsule structure and assembly with a hydroxylamine-armed fluorescent probe

C. Crawford, R. J. B. Cordero, L. Guazzelli, M. P. Wear, S. Oscarson, A. Casadevall

This study uses a hydroxylamine-armed fluorescent probe to investigate the structure and assembly of the Cryptococcus neoformans capsule, revealing reducing ends at the cell wall surface.

bioRxiv · Dec 11, 2019Microbiology