Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosis
A. Balasubramanian, L. Ghimire, A. Y. Hsu…·H. R. Luo
The paper identifies palmitoylation of GSDMD at Cys191/Cys192 as essential for its membrane translocation and pore-forming activity in macrophages.