BioengineeringbioRxiv
Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression injury
R. D. Gonzalez-Cruz, Y. Wan, D. Calvao…·D. Hoffman-Kim
The paper presents an in vitro model of sustained compressive neural injury using cortical spheroids and shows increased DNA damage and microtubule degradation under higher compressive strain.
DOI 10.1371/journal.pone.0295086