Cancer BiologyJCI InsightPeer-reviewed
Unbalancing cAMP and Ras/MAPK pathways as a therapeutic strategy for cutaneous neurofibromas
H. Mazuelas, M. Magallon-Lorenz, I. Uriarte-Arrazola…·E. Serra
This study identifies a therapeutic strategy for cutaneous neurofibromas by combining a MEKi and a cAMP elevator to disrupt SC-FB crosstalk and inhibit tumor growth.
DOI 10.1172/jci.insight.168826