Author

H. Moore

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Miskalis· 1 shared A. Nambiar· 1 shared A. Smith· 1 shared A. Zeballos· 1 shared Anne H. FreeliniD· 1 shared Ashwinikumar KulkarniiD· 1 shared B. Granger· 1 shared Bradley Charles LegaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBioengineering

A. Miskalis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Stimulation modulates cell assemblies linked with gene networks in the human temporal cortex ex vivo

H. Moore, Mantre Dehnad, Anne H. Freelin, B. Granger, S. Subramanian, Ashwinikumar Kulkarni, Stefano Berto, Bradley Charles Lega, Geneviève Konopka

The paper shows that stimulation increases firing rates in pyramidal cells and strengthens cell assemblies in the human temporal cortex, linked to gene networks involving excitatory neurons and non-neurons.

bioRxiv · Jun 25, 2025 · PreprintNeuroscience

SPLICER: A Highly Efficient Base Editing Toolbox That Enables In Vivo Therapeutic Exon Skipping

A. Miskalis, S. Shirguppe, J. Winter, G. Elias, D. Swami, A. Nambiar, M. Stilger, W. Woods, N. Gosstola, M. Gapinske, A. Zeballos, H. Moore, S. Maslov, T. Gaj, P. Perez-Pinera

SPLICER improves exon skipping by editing both splice acceptor and donor sites, reducing aberrant splicing and enabling therapeutic applications in Alzheimer's disease.

bioRxiv · Apr 1, 2024 · PreprintBioengineering

tRNA Methylation Resolves Codon Usage Bias at the Limit of Cell Viability

I. Masuda, Y. Yamaki, R. Detroja, S. Tagore, H. Moore, S. Maharjan, Y. Nakano, T. Christian, R. Matsubara, T. M. Lowe, M. Frenkel-Morgenstern, Y.-M. Hou

This study shows that m1G37 tRNA modification neutralizes differential proline codon decoding, and its absence requires a minor isoacceptor for E. coli viability.

bioRxiv · May 14, 2022Microbiology

GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells

L. Vitillo, C. Durance, Z. Hewitt, H. Moore, A. Smith, L. Vallier

This paper presents a GMP-compliant protocol to derive and differentiate clinical-grade human embryonic stem cells into neuroepithelial stem cells with neurogenic potential.

bioRxiv · Apr 22, 2020Cell Biology