A. Nambiar

SPLICER: A Highly Efficient Base Editing Toolbox That Enables In Vivo Therapeutic Exon Skipping

SPLICER improves exon skipping by editing both splice acceptor and donor sites, reducing aberrant splicing and enabling therapeutic applications in Alzheimer's disease.

Upstream regulator of genomic imprinting in rice endosperm is a small RNA-associated chromatin remodeler

This study identifies OsCLSY3 as an essential chromatin remodeler for rice endosperm development and imprinting, regulated by RNA-directed DNA methylation and critical for small RNA production and imprinted gene expression.

Investigating Transfusion-Related Sepsis using Culture-Independent Metagenomic Sequencing

This study uses metagenomic sequencing to identify pathogens in transfusion-related sepsis cases, revealing a novel Acinetobacter species and demonstrating the utility of culture-independent methods.

Transcription factor NF-κB in a basal metazoan, the sponge, has conserved and unique sequences, activities, and regulation

This study characterizes the NF-κB protein in the sponge Amphimedon queenslandica, showing conserved features with vertebrates but distinct regulatory mechanisms.