H. P. Bogerd

This study examines the non-specific binding of three drug-like compounds to HIV-1 stem-loop RNAs, showing they inhibit RNA function and exhibit off-target interactions.

This study shows HIV-1 can replicate robustly without integrase function in cells expressing HTLV-1 Tax, forming transcriptionally active episomal DNA circles that avoid epigenetic silencing.

The paper develops a method to assess RNA excited-state stability and abundance in cells using mutations and applies it to HIV-1 regulatory RNAs, showing ESs form with comparable abundance in vitro and in vivo.

This study shows that murine leukemia virus (MLV) transcripts have high levels of m6A, m5C, and Nm modifications, which enhance viral replication and gene expression.