ImmunologybioRxiv
Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons
D. X. Ji, K. C. Witt, D. I. Kotov…·R. E. Vance
This study identifies SP140 as a repressor of type I interferons that enhances resistance to bacterial infections like Legionella pneumophila and Mycobacterium tuberculosis.
DOI 10.7554/elife.67290