Author

H. Sekiguchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Kuramochi· 2 shared M. Sato· 2 shared S. Aiso· 2 shared S. K. Kondoh· 2 shared S. Watanabe· 2 shared T. Yagi· 2 shared Y. Asao· 2 shared Y. C. Sasaki· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

M. Kuramochi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals using a photoacoustic imaging scanner with a hemispherical detector array

Y. Asao, R. Hirano, K. Nagae, H. Sekiguchi, S. Aiso, S. Watanabe, M. Sato, T. Yagi, S. K. Kondoh

This study uses photoacoustic imaging to visualize oxygen saturation distribution in mice, showing changes in hemoglobin oxygen saturation in normal and tumor vessels over time.

bioRxiv · Jun 19, 2023 · PreprintBioengineering

In vivo label-free observation of tumor-related blood vessels in small animals using a newly designed photoacoustic 3D imaging system

Y. Asao, K.-i. Nagae, K. Miyasaka, H. Sekiguchi, S. Aiso, S. Watanabe, M. Sato, S. K. Kondoh, Y. Nakajima, K. Kishi, T. Yagi

This study demonstrates a photoacoustic 3D imaging system for non-invasive visualization of tumor-related blood vessels in small animals.

bioRxiv · Nov 9, 2021Cancer Biology

Structural basis for the coiled-coil architecture of human CtIP

C. R. Morton, N. J. Rzechorzek, J. D. Maman, M. Kuramochi, H. Sekiguchi, R. P. Rambo, Y. C. Sasaki, O. R. Davies, L. Pellegrini

This study presents an atomic model of human CtIP's structure, revealing its extended dimer-of-dimers architecture and dynamic zinc-binding motif involved in DNA repair.

bioRxiv · Mar 5, 2021Biophysics

Agonist and antagonist diverted twisting motions of single TRPV1 channel

S. Fujimura, K. Mio, M. Kuramochi, H. Sekiguchi, I. Keigo, M. Mio, K. Hengphasatporn, Y. Shigeta, T. Kubo, Y. C. Sasaki

The paper uses DXT to observe agonist and antagonist-induced rotational biases in TRPV1 channels, revealing opposing twisting motions and providing insights into TRP channel activation and modulation.

bioRxiv · Aug 18, 2020Biophysics