H. Smith

Operational lessons learned from simulating an elimination response to a transboundary animal disease in wild animals

The paper simulates a TAD control effort in wild pigs to identify operational challenges and propose solutions for rapid population reduction during a hypothetical outbreak.

Non-antibiotic pharmaceuticals exhibit toxicity against Escherichia coli at environmentallyrelevant concentrations with no evolution of cross-resistance to antibiotics

This study shows non-antibiotic pharmaceuticals inhibit E. coli growth at environmental concentrations without promoting cross-resistance to antibiotics.

Oxidized phospholipid oxPAPC induces a Th1-like phenotype in regulatory T cells and inhibits their protective function in atherosclerosis

This study shows that oxPAPC induces a Th1-like phenotype in Tregs, reduces their viability, and impairs their ability to suppress atherosclerosis in mice.

Seasonal polyphenism of wing colors and its influence on sulphur butterfly diversification

This study shows seasonal polyphenism in Zerene cesonia butterflies driven by temperature and photoperiod, with genetic links to color plasticity and implications for speciation in sulphur butterflies.

A secreted proteomic footprint for stem cell pluripotency

The paper identifies a proteomic signature associated with early loss of pluripotency in human stem cells and demonstrates its diagnostic potential using multiplexed biomarkers.

Cell-intrinsic IL4R alpha independence of large intestinal RELMα+ Ym1+ macrophages

This study shows that RELMα+ Ym1+ macrophages in the large intestine can upregulate these markers without IL4R signaling, challenging the idea that IL4/IL13 is required for their activation.

Integrated Metabolomics, Transcriptomics, and Signal Protein Profile Define the Effector Function and Associated Metabotype of Five Polarized Macrophage Phenotypes

Metagenomic data reveal diverse fungal and algal communities associated with the lichen symbiosis

The paper analyzes metagenomic data to characterize fungal communities in lichens, revealing diversity and previously unknown associations.

In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection

The paper designs a T-cell epitope vaccine candidate for Trichuris trichiura using in silico epitope prediction and virus-like particle delivery, showing reduced worm burden and immune responses in mice.

Tragedy Of The Commons In The Chemostat

The paper demonstrates the tragedy of the commons in a chemostat model with cooperator and cheater species, showing both go extinct when the cheater is present.