K. Evans

Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty

This study investigates the distinct roles of vlOFC and BLA in stimulus- and action-based reversal learning under uncertainty using chemogenetic inhibition in rats.

Phylogenomics reveals the deep ocean as an accelerator for evolutionary diversification in anglerfishes

This study uses phylogenomic and phenotypic data to show that deep-sea anglerfishes have greater diversity and faster diversification rates than shallow-water relatives, challenging expectations about habitat constraints.

Overconfidence undermines global wildlife abundance trends

The paper shows current abundance trend estimates are unreliable due to unaccounted phylogenetic, spatial, and temporal structures, and introduces a new framework to improve accuracy and uncertainty estimation.

Seasonal polyphenism of wing colors and its influence on sulphur butterfly diversification

This study shows seasonal polyphenism in Zerene cesonia butterflies driven by temperature and photoperiod, with genetic links to color plasticity and implications for speciation in sulphur butterflies.

Structure and function of N-acetylglucosamine kinase illuminates the catalytic mechanism of ROK kinases

The paper determines the structure of NagK from Plesiomonas shigelloides in complex with GlcNAc and ATP analogue, revealing conformational changes and a sequential random mechanism.

Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration

The paper identifies an IL-1β-Notch-Fosl2 axis that regulates differentiation plasticity of airway progenitors during alveolar regeneration.

Molecular underpinnings of ssDNA specificity by Rep HUH endonucleases and implications for HUH-tag multiplexing and engineering

The paper investigates the molecular mechanism of ssDNA specificity by HUH-endonucleases and demonstrates how this can be engineered for multiplexed HUH-tagging and bioconjugation.

A highly multiplexed melt-curve assay for detecting the most prevalent carbapenemase, ESBL and AmpC genes

The paper develops a highly multiplexed HRM assay to detect ESBL, carbapenemase, and AmpC genes in Gram-negative bacteria with high sensitivity and specificity.

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

This study identifies unique molecular features of MDSCs using single-cell transcriptomics, revealing a distinct maturation trajectory and novel surface markers for their detection.

Drought adaptation in nature by extensive genetic loss-of-function

The paper identifies gene knockouts linked to drought adaptation in Arabidopsis thaliana using whole genome sequences and satellite data, showing their adaptive value.