Electrode sharpness and insertion speed reduce tissue damage near high-density penetrating arrays
I. N. McNamara, S. M. Wellman, L. Li, J. R. Eles, S. Savya, H. Sohal, M. Angle, T. D. Y. Kozai
This study evaluates how electrode sharpness and insertion speed affect tissue damage when implanting high-density neural arrays in mice and rats, finding that electro-sharpened arrays and faster insertion reduce cellular damage and BBB compromise.
bioRxiv · Nov 22, 2023 · PreprintBioengineering