Author

T. Tsaava

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1

Frequent Co-Authors

K. J. Tracey· 4 shared E. H. Chang· 3 shared S. S. Chavan· 3 shared H. A. Silverman· 2 shared M. E. Addorisio· 2 shared M. Gunasekaran· 2 shared U. Andersson· 2 shared A. Devarajan· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

K. J. Tracey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Flexible IrOx Neural Electrode for Mouse Vagus Nerve Stimulation

T. Sun, T. Tsaava, J. Peragine, C. Crosfield, M. F. Lopez, R. Modi, R. Sharma, C. Li, H. Sohal, E. H. Chang, L. Rieth

This paper develops and evaluates a flexible IrOx electrode for mouse vagus nerve stimulation, showing it remains functional under high stimulation and induces reliable physiological responses.

bioRxiv · Oct 12, 2022 · PreprintBioengineering

Focused Ultrasound Modulation of Hepatic Neural Plexus Restores Glucose Homeostasis in Diabetes

V. Cotero, H. MIWA, Z. Hirschstein, K. Qanud, T. Huerta, N. Tai, Y. Ding, K. Jimenez-Cowell, J.-N. Tomaio, W. Song, A. Devarajan, T. Tsaava, J. F. Graf, R. Madhavan, K. Wallace, , C. Puleo

The paper demonstrates that focused ultrasound activation of the hepatic neural plexus restores glucose homeostasis in diabetes models across multiple species.

bioRxiv · Apr 16, 2021 · PreprintBiophysics

Serum cytokine levels are modulated by specific frequencies, amplitudes, and pulse widths of vagus nerve stimulation

T. Tsaava, T. Datta-Chaudhuri, M. E. Addorisio, E. B. Masi, H. A. Silverman, J. E. Newman, G. H. Imperato, C. E. Bouton, K. J. Tracey, S. S. Chavan, E. H. Chang

This study shows that specific electrical stimulation parameters of the vagus nerve can modulate serum cytokine levels in healthy mice without inducing inflammation.

bioRxiv · Jan 8, 2020 · PreprintImmunology

Antibody responses to immunization require sensory neurons

A. Tynan, T. Tsaava, M. Gunasekaran, I. Snee, T. Mak, P. Olofsson, U. Andersson, S. S. Chavan, K. J. Tracey

This study shows that TRPV1-expressing sensory neurons are required for antibody responses to novel antigens and that stimulating these neurons enhances antibody production.

bioRxiv · Nov 30, 2019 · PreprintImmunology

Transient Receptor Potential Ankyrin 1 Mediates Afferent Signals in the Inflammatory Reflex

H. A. Silverman, M. Gunasekaran, E. H. Chang, Q. Chang, M. E. Addorisio, A. Stiegler, A. M. Kressel, J. H. Li, T. Tsaava, T. S. Huerta, V. A. Pavlov, U. Andersson, S. S. Chavan, K. J. Tracey

This study identifies TRPA1 in vagus neurons as essential for detecting IL-1β to initiate the inflammatory reflex, reducing inflammation and improving survival in sepsis.

bioRxiv · Nov 4, 2019 · PreprintPhysiology