Author

H. Staley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. G. Tansey· 3 shared N. Neighbarger· 2 shared R. Wallings· 2 shared B. C. Murray· 1 shared B. M. Moore· 1 shared C. Achat-Mendes· 1 shared C. Klein· 1 shared C. McLaughlin· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. G. Tansey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses

R. Wallings, D. A. Gillett, H. Staley, S. Mahn, J. Mark, N. Neighbarger, H. kordasiewicz, W. D. Hirst, M. G. Tansey

This study shows that reducing GPNMB in progranulin-deficient myeloid cells impairs lysosomal function and immune responses, suggesting GPNMB is essential for maintaining immune homeostasis.

bioRxiv · Jul 22, 2024 · PreprintImmunology

The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner

R. Wallings, K. McFarland, H. Staley, N. Neighbarger, S. Schaake, N. Brueggemann, S. Zittel, T. Usnich, C. Klein, E. Sammler, M. G. Tansey

The R1441C-LRRK2 mutation leads to age-dependent immune cell exhaustion in macrophages, with sex-specific effects observed in mice and human patients.

bioRxiv · Oct 12, 2023Immunology

Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

V. Joers, B. C. Murray, C. McLaughlin, D. Oliver, H. Staley, J. E. Coronado, C. Achat-Mendes, S. Golshani, S. D. Kelly, M. Goodson, D. Lee, F. P. Manfredsson, B. M. Moore, M. G. Tansey

This study shows that targeting CB2 with SMM-189 reduces alpha-synuclein aggregates and neuroinflammation in a rat model of Parkinson's disease.

bioRxiv · Aug 25, 2023Immunology