Exploiting Epigenetic Targets to Overcome Taxane Resistance in Prostate Cancer
B. Cevatemre, I. Bulut, B. Dedeoglu, A. Isiklar, H. Syed, O. Yedier Bayram, T. Bagci-Onder, C. Acilan Ayhan
This study identifies BRPF reader proteins and epigenetic regulators as targets to overcome taxane resistance in prostate cancer by reversing ABCB1-mediated efflux and restoring taxane susceptibility.
bioRxiv · Aug 10, 2023Cancer Biology