Cell BiologybioRxiv
Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes
I. Dereli, V. Telychko, F. Papanikos…·A. Toth
The paper identifies IHO1-HORMAD1 as essential for seeding the meiotic DSB machinery on chromosome axes, ensuring sufficient DSBs for homologous chromosome pairing in mice.
DOI 10.1038/s41467-024-47020-1