Author

F. Herzog

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:yeast· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

G. Hagemann· 3 shared M. Potocnjak· 3 shared S. Singh· 2 shared A. Akhmanova· 1 shared A. Bondarieva· 1 shared A. J. R. Heck· 1 shared A. M. V. West· 1 shared A. Schnittger· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersBiochemistry

G. Hagemann

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Author profile →

6 papers

Recent·Most cited

Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes

I. Dereli, V. Telychko, F. Papanikos, K. Raveendran, J. Xu, M. Boekhout, M. Stanzione, B. Neuditschko, N. S. Imjeti, E. Selezneva, H. T. Erbasi, S. Demir, T. Giannattasio, M. Gentzel, M. Stevense, , A. Toth

The paper identifies IHO1-HORMAD1 as essential for seeding the meiotic DSB machinery on chromosome axes, ensuring sufficient DSBs for homologous chromosome pairing in mice.

bioRxiv · Nov 27, 2023Cell Biology

Quantitative crosslinking and mass spectrometry determine binding interfaces and affinities mediating kinetochore stabilization

G. Hagemann, V. Solis-Mezarino, S. Singh, M. Potocnjak, C. Kumar, F. Herzog

This study uses quantitative XLMS to determine binding interfaces and affinities in the kinetochore complex, showing phosphorylation reduces KD values by ~200-fold, essential for cell viability.

bioRxiv · Mar 31, 2022 · PreprintBiochemistry

Microtubule plus-end regulation by centriolar cap proteins

F. E. Ogunmolu, S. Moradi, V. A. Volkov, C. van Hoorn, J. Wu, N. Andrea, S. Hua, K. Jiang, I. A. Vakonakis, M. Potocnjak, F. Herzog, B. Gigant, N. Gudimchuk, K. E. Stecker, M. Dogterom, , A. Akhmanova

The paper investigates how CP110 and CEP97 regulate microtubule plus-end dynamics and centriole biogenesis through direct interactions and synergistic effects.

bioRxiv · Dec 29, 2021 · PreprintCell Biology

The COMA complex is required for positioning Ipl1 activity proximal to Cse4 nucleosomes in budding yeast

J. Fischboeck, S. Singh, M. Potocnjak, G. Hagemann, V. Solis, S. Woike, M. Ghodgaonkar, J. Andreani, F. Herzog

This study investigates the COMA complex's role in positioning Ipl1Aurora B kinase near Cse4 nucleosomes in budding yeast, revealing its importance for kinetochore function.

eLife · May 21, 2019Peer-reviewedCell Biology

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

C. Iacobucci, C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, C. Borchers, N. I. Brodie, J. E. Bruce, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, G. Degliesposti, M. Q. Dong, N. Edinger, , Rand

This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.

bioRxiv · Sep 26, 2018 · PreprintBiochemistry

A conserved mechanism for meiotic chromosome organization through self-assembly of a filamentous chromosome axis core

A. M. V. West, S. C. Rosenberg, S. N. Ur, M. K. Lehmer, Q. Ye, G. Hagemann, I. Caballero, I. Uson, F. Herzog, K. D. Corbett

The paper identifies conserved axis core proteins across species and shows they form filamentous structures essential for meiotic chromosome organization and recombination.

bioRxiv · Jul 24, 2018 · PreprintBiochemistry