Cancer BiologybioRxivPreprint
Prediction of Resistant Mutations against Upcoming ALK-TKIs, Repotrectinib (TPX-0005) and Ensartinib (X-396)
Y. Doi, H. Tagaya, A. Noge, K. Semba
The paper predicts resistant mutations against new ALK-TKIs, repotrectinib and ensartinib, using an error-prone PCR-based system, suggesting their potential as second-line treatments after alectinib.
DOI 10.1101/2022.05.26.493531