BiochemistrybioRxiv
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
Y. Sun, T. J. Florio, S. Gupta…·N. G. Sgourakis
This paper determines the structure of a peptide-centric Chimeric Antigen Receptor (PC-CAR) complex and identifies structural principles for antigen recognition across multiple HLA allotypes.
DOI 10.1126/sciimmunol.adj5792