Author

A. Farrel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

J. M. Maris· 2 shared M. Yarmarkovich· 2 shared A. J. Wolpaw· 1 shared B. R. Kiefel· 1 shared C. V. Dang· 1 shared E. Mycek· 1 shared F. Zammarchi· 1 shared G. F. Papadaki· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

J. M. Maris

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets

N. M. Kendsersky, M. Odrobina, N. W. Mabe, A. Farrel, L. Grossmann, M. Tsang, A. J. Wolpaw, F. Zammarchi, P. H. van Berkel, C. V. Dang, Y. P. Mosse, K. Stegmaier, J. Maris

This paper identifies cell state-dependent and -independent immunotherapeutic targets in neuroblastoma by analyzing subtype-specific gene expression and validating targets through experimental methods.

bioRxiv · Jun 27, 2024Cancer Biology

Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion

Y. Sun, T. J. Florio, S. Gupta, M. C. Young, Q. F. Marshall, S. E. Garfinkle, G. F. Papadaki, H. V. Truong, E. Mycek, P. Li, A. Farrel, N. L. Church, S. Jabar, M. D. Beasley, B. R. Kiefel, , N. G. Sgourakis

This paper determines the structure of a peptide-centric Chimeric Antigen Receptor (PC-CAR) complex and identifies structural principles for antigen recognition across multiple HLA allotypes.

bioRxiv · May 24, 2023Biochemistry

A SARS-CoV-2 Vaccination Strategy Focused on Population-Scale Immunity

M. Yarmarkovich, J. M. Warrington, A. Farrel, J. M. Maris

This paper proposes a SARS-CoV-2 vaccination strategy targeting conserved viral regions and MHC-presented epitopes to induce broad immunity.

bioRxiv · Mar 31, 2020Immunology