ImmunologybioRxiv
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
O. Tsyklauri, T. Chadimova, V. Niederlova…·O. Stepanek
This study identifies Tregs suppressing KLRK1+ IL7R+ CD8+ effector T cells by limiting IL-2, which enhances autoimmunity and anti-tumor responses.
DOI 10.7554/elife.79342