Author

J. Michalik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Drobek· 3 shared O. Stepanek· 3 shared A. Neuwirth· 2 shared S. Janusova· 2 shared V. Niederlova· 2 shared A. Moudra· 1 shared D. Cizkova· 1 shared D. Paprckova· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersImmunology

A. Drobek

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Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivOct 25, 2023

ABIN1 is a negative regulator of effector functions in cytotoxic T cells

S. Janusova, D. Paprckova, J. Michalik…·O. Stepanek

This study identifies ABIN1 as a negative regulator of effector functions in cytotoxic T cells, showing its role in suppressing NF-κB and p38 pathways.

DOI 10.1038/s44319-024-00179-6

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivNov 10, 2021

Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2

O. Tsyklauri, T. Chadimova, V. Niederlova…·O. Stepanek

This study identifies Tregs suppressing KLRK1+ IL7R+ CD8+ effector T cells by limiting IL-2, which enhances autoimmunity and anti-tumor responses.

DOI 10.7554/elife.79342

mouseflow cytometry

𝕏 PostBluesky

ImmunologybioRxivSep 1, 2020

Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

A. Moudra, V. Niederlova, J. Novotny…·O. Stepanek

This study characterizes antigen-inexperienced memory-like T cells across genetic backgrounds, hygienic conditions, and aging, showing their clonal stability and distinct subsets defined by CD122 expression.

DOI 10.4049/jimmunol.2001028

mousebulk RNA-seq

𝕏 PostBluesky