S100A8/A9 mediate the reprograming of normal mammary epithelial cells induced by dynamic cell-cell interactions with adjacent breast cancer cells.
S. H. Jo, W. H. Heo, M. Quan, B. S. Hong, J. H. Kim, H.-B. Lee, W. Han, Y. Park, D.-S. Lee, N. H. Kwon, M. C. Park, J. Chae, J.-I. Kim, D.-Y. Noh, H.-G. Moon
This study shows that S100A8/A9 mediates the reprogramming of normal mammary epithelial cells by dynamic interactions with breast cancer cells, leading to epithelial-mesenchymal transition and altered cellular behaviors.
bioRxiv · May 2, 2020Cancer Biology