Haoyu Li

This paper introduces SIM-fdFLIM, a super-resolution FLIM method that preserves ratio accuracy and enables high-speed, high-resolution live-cell lifetime imaging.

The paper introduces COMET, a lightweight head-mounted mesoscope for cortex-wide single-cell calcium imaging in freely moving mice, demonstrating its ability to capture neural activity during natural behaviors.

The paper identifies an ISR-HCN2 cholinergic mechanism in nucleus accumbens interneurons that sustains maladaptive cue-driven motivation and shows HCN blockade reduces cue-seeking behavior.

This paper introduces CLG, a structural-functional calibration method for volumetric calcium imaging that corrects neuron identity errors, reducing duplicate counts and improving network analysis accuracy.

This paper introduces FLAME, a high-throughput 3D ultrasound imaging technique that significantly improves resolution and speed for microvascular imaging in mouse organs.