Cell BiologyNeurobiology of DiseasePeer-reviewed
Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress
Hannah C. Leeson, Julio Aguado, Cecilia Gómez‐Inclán…·Ernst Jurgen Wolvetang
This study uses patient-derived iPSCs and organoids to show mitochondrial dysfunction and oxidative stress in AT, which can be mitigated by ATM correction or antioxidants.