Julio Aguado

This study shows that micro- and nanoplastics disrupt human brain development and function by inducing inflammation, cellular senescence, and altered electrophysiological activity.

The paper shows microbial amyloids from gut pathogens can trigger microglial hyperactivity and neuroinflammation, contributing to Alzheimer's disease progression.

This study uses patient-derived iPSCs and organoids to show mitochondrial dysfunction and oxidative stress in AT, which can be mitigated by ATM correction or antioxidants.

This study shows senolytic drugs reduce brain aging and COVID-19-related neuropathology by targeting senescent cells in human brain organoids and mice.

This study shows that rapamycin reduces VPA-induced teratogenic effects by suppressing AP-1-mediated senescence in human and zebrafish models.

This study identifies three distinct senescent subpopulations in human mesenchymal stem cells using single-cell RNA sequencing, revealing potential drug targets for senescence delay.