Cancer BiologyNature CommunicationsPeer-reviewed
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
Hannah L. Mackay, Helen R Stone, George E. Ronson…·Joanna R. Morris
This study identifies USP50 as a ubiquitin-binding protein that regulates helicase and nuclease activities during DNA replication to prevent fork collapse and maintain genomic stability.
5 citations