Cancer BiologyNeuro-OncologyPeer-reviewed
Standard treatment against paediatric BRAF-V600E glioma promotes senescence and sensitizes tumours to BCL-xL inhibition
Romain Guiho, Hiba Hamdi, Grace Cooksley…·Juan Pedro Martinez Barbera
This study shows that standard therapies for paediatric BRAF-V600E glioma induce senescence, which can be targeted by BCL-xL inhibitors to prevent tumour regrowth.
DOI 10.1093/neuonc/noag270