BioengineeringBiotechnology ProgressPeer-reviewed
Sequential, Chromosome-Specific Glutamine Synthetase Double Knockout with Cas-CLOVER Establishes Enhanced CHO Platforms for Cell Line Development
Cintia Elisabeth Gomez Limia, Valeriya Steffey, Hsueh Che Cheng…·Jack Crawford
This study uses Cas-CLOVER to create a double glutamine synthetase knockout CHO cell line with enhanced productivity for biopharmaceutical production.
DOI 10.1002/btpr.70113