MicrobiologybioRxiv
High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity.
R. Choi, M. Zhou, R. Shek…·W. C. Van Voorhis
The paper screens drug libraries to find inhibitors of SARS-CoV-2 nsp15 endoribonuclease, identifying Exebryl-1 as a potential antiviral compound.
DOI 10.1371/journal.pone.0250019