Cell BiologybioRxiv
Inhibitors of the Bub1 spindle assembly checkpoint kinase: Synthesis of BAY-320 and comparison with 2OH-BNPP1
I. Amalina, H. Whalley, D. Perera…·S. S. Taylor
This study compares two Bub1 kinase inhibitors, finding that BAY-320 inhibits Bub1 in vivo but with high concentrations and potential off-target effects, while 2OH-BNPP1 is ineffective.
DOI 10.1098/rsos.210854