Cell BiologybioRxiv
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
DOI 10.1172/jci157504
Author
J. Poulton
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2019-2021 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 26 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Animal Behavior & CognitionbioRxiv
Therapeutic doses of paracetamol with co-administration of cysteine and mannitol during early development result in long term behavioral changes in laboratory rats.
N. Suda, J. Cendejas-Hernandez, J. Poulton…·W. Parker
This study shows that therapeutic paracetamol doses with antioxidants during early rat development cause long-term behavioral changes, indicating oxidative stress mediators do not fully prevent neurodevelopmental effects.
DOI 10.1371/journal.pone.0253543 - Cell BiologybioRxiv
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations in vivo
Y.-T. Liu, X. Huang, D. Nguyen…·D. P. Narendra
This study shows that loss of CHCHD2 and CHCHD10 activates OMA1, leading to mitochondrial cristae disruption similar to patient mutations, linking C10 pathogenesis to C2/C10 function.
DOI 10.1093/hmg/ddaa077