Cell BiologybioRxiv
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.
I. Fernandez Duran, N. Tarrats, J. Birch…·J. C. Acosta
This study shows that caspase-4 non-canonical inflammasome activation by LPS induces cellular senescence and contributes to oncogene-induced senescence and tumour suppression.
DOI 10.1038/s41418-021-00917-6