Cancer BiologybioRxiv
On-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape
S. A. Malaker, J. Quanico, A. Raffo Romero…·M. Salzet
This paper develops a spatially-resolved glycoproteomics approach combining MALDI imaging and LC-MS/MS to identify glycan patterns in canine gliomas, revealing dysregulated glycosylation in tumor and necrotic regions.
DOI 10.1016/j.chembiol.2021.05.007