Author

I. Jongerius

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Dhillon· 1 shared A. Kamp· 1 shared A. Spaan· 1 shared A. Tromp· 1 shared C. J. C. de Haas· 1 shared D. Roem· 1 shared E. C. Heezius· 1 shared e. furlong· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Dhillon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular basis for B. pertussis interference with complement, coagulation, fibrinolytic and contact activation systems: The cryo-EM structure of the Vag8-C1 inhibitor complex

A. Dhillon, J. Deme, e. furlong, D. Roem, I. Jongerius, S. Johnson, S. M. Lea

The paper determines the cryo-EM structure of the Vag8-C1-INH complex, revealing how Vag8 disrupts C1-INH function by sequestering its Reactive Centre Loop.

bioRxiv · Oct 5, 2020Microbiology

Unravelling the effect of a potentiating anti-Factor H antibody on atypical hemolytic uremic syndrome associated factor H variants

G. Dekkers, M. Brouwer, J. Jeremiasse, A. Kamp, R. M. Biggs, G. van Mierlo, S. Lauder, S. Katti, T. W. Kuijpers, T. Rispens, I. Jongerius

This study investigates how a potentiating anti-FH antibody enhances the function of wild-type and aHUS-associated FH variants.

bioRxiv · Apr 8, 2020 · PreprintImmunology

Bacterial immune evasion proteins: The therapeutic potential of CHIPS

A. Tromp, Y. Zhao, I. Jongerius, E. C. Heezius, P. Abrial, M. Ruyken, J. van Strijp, C. J. C. de Haas, A. Spaan, K. P. M. van Kessel, T. Henry, P.-J. A. Haas

This study evaluates CHIPS as a therapeutic agent for inflammation, showing promise in mice but safety concerns in humans due to pre-existing antibodies.

bioRxiv · Feb 25, 2020 · PreprintMicrobiology