Author

A. Dhillon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Dufour· 1 shared A. Hoque· 1 shared A. Kadek· 1 shared A. Katzourakis· 1 shared A. N. Volkov· 1 shared B. D. Persson· 1 shared C. Roulston· 1 shared C. Uetrecht· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Dufour

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural Insights into the Interaction Between Adenovirus C5 Hexon and Human Lactoferrin

A. Dhillon, B. D. Persson, A. N. Volkov, H. Sulzen, A. Kadek, P. Pompach, S. Kereiche, M. Lepsik, K. Danskog, C. Uetrecht, N. Arnberg, S. Zoll

This study presents cryo-EM structures of HAdV-5C hexon and its complex with human lactoferrin, revealing molecular interactions critical for viral entry.

bioRxiv · Oct 9, 2023Biochemistry

Investigating the evolutionary origins of the first three SARS-CoV-2 variants of concern

M. Ghafari, Q. Liu, A. Dhillon, A. Katzourakis, D. Weissman

This study investigates the evolutionary origins of the first three SARS-CoV-2 variants of concern, finding that they likely evolved within long-term infections in single individuals through multiple mutations.

bioRxiv · May 9, 2022Evolutionary Biology

Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death

L. J. Jenkins, I. Y. Luk, M. Palmieri, W. D. Fairlie, E. F. Lee, K. L. Schoffer, T. Tan, I. Ng, N. Vukelic, J. W. Tse, R. Nightingale, Z. Alam, G. Iatropoulos, M. Ernst, S. Afshar-Sterle, , J. M. Mariadason

This study shows that combining MEK/ERK and HDAC inhibition synergistically induces apoptosis in colorectal cancer cells and organoids, and can be tailored to specific MAPK genotypes.

bioRxiv · Feb 15, 2021 · PreprintCancer Biology

Molecular basis for B. pertussis interference with complement, coagulation, fibrinolytic and contact activation systems: The cryo-EM structure of the Vag8-C1 inhibitor complex

A. Dhillon, J. Deme, e. furlong, D. Roem, I. Jongerius, S. Johnson, S. M. Lea

The paper determines the cryo-EM structure of the Vag8-C1-INH complex, revealing how Vag8 disrupts C1-INH function by sequestering its Reactive Centre Loop.

bioRxiv · Oct 5, 2020Microbiology

An Atlas of Phosphorylation and Proteolytic Processing Events During Excitotoxic Neuronal Death Reveals New Therapeutic Opportunities

S. S. Ameen, A. Dufour, M. I. Hossain, A. Hoque, S. Sturgeon, H. Nandurkar, D. Draxler, R. Medcalf, M. A. Kamaruddin, I. Lucet, M. Leeming, D. Liu, A. Dhillon, J. P. Lim, H. Zhu, , H. C. Cheng

The paper uses proteomic approaches to identify proteins modified during excitotoxic neuronal death and shows that blocking Src kinase protects neurons in a rat model.

bioRxiv · Jun 15, 2020 · PreprintBiochemistry