E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members
J. M. Bugter, P. van Kerkhof, E. Janssen…·M. M. Maurice
This study shows RNF43 and ZNRF3 differentially regulate endocytosis of specific Frizzled family members through their transmembrane domains, linking these differences to cancer mutation patterns.