Author

A. Merenda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B.-K. Koo· 2 shared M. M. Maurice· 2 shared A. Catala-Bordes· 1 shared A. R. Keijzer· 1 shared A.-D. Bamford· 1 shared C. Jamieson· 1 shared D. Xanthakis· 1 shared F. C. P. Holstege· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

B.-K. Koo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway

S. F. Plugge, H. Ma, J. Y. van der Vaart, J. Sprangers, F. H. M. Morsink, D. Xanthakis, C. Jamieson, K. B. W. Stroot, A. R. Keijzer, T. Margaritis, T. Candelli, R. Straver, J. de Ridder, F. C. P. Holstege, W. W. J. de Leng, , M. M. Maurice

This study shows that LKB1 loss in intestinal cells leads to a pre-malignant state linked to serrated colorectal cancer, which is amplified by loss-of-heterozygosity.

bioRxiv · Jul 17, 2023 · PreprintCancer Biology

Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2

G. Colozza, H. Lee, A. Merenda, S.-H. Wu, A. Catala-Bordes, T. Radaszkiewicz, I. Jordens, J.-H. Lee, A.-D. Bamford, F. Farnhammer, T. Y. Low, M. M. Maurice, V. Bryja, J. Kim, B.-K. Koo

This study identifies Daam1/2 as a regulator of Wnt signaling that is essential for Paneth cell differentiation and intestinal stem cell homeostasis.

bioRxiv · Jan 24, 2023Cell Biology

Norovirus replication in human intestinal epithelial cells is restricted by the interferon-induced JAK/STAT signalling pathway and RNA Polymerase II mediated transcriptional responses.

M. T. Hosmillo, Y. Chaudhry, K. Nayak, F. Sorgeloos, B.-K. Koo, A. Merenda, R. Lillestol, L. Drumright, M. Zilbauer, I. G. Goodfellow

This study shows that HuNoV replication in intestinal epithelial cells is restricted by IFN-induced transcriptional responses and that inhibiting these responses enhances viral replication.

bioRxiv · Aug 10, 2019 · PreprintMicrobiology