Author

E. Janssen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

I. Jordens· 2 shared J. M. Bugter· 2 shared M. M. Maurice· 2 shared B.-K. Koo· 1 shared C. Jamieson· 1 shared C. Scheidegger· 1 shared D. Iglesias van Montfort· 1 shared D. Irvine· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

I. Jordens

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lithic bacterial communities: ecological aspects focusing on Tintenstrich communities

F. Pittino, J. Oliveira, S. Fink, E. Janssen, C. Scheidegger

The paper characterizes Tintenstrich bacterial communities on different rock substrates using Illumina sequencing and multivariate models, revealing Cyanobacteria and Proteobacteria as dominant phyla and differences in diversity based on substrate type.

bioRxiv · Apr 30, 2024 · PreprintMicrobiology

E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members

J. M. Bugter, P. van Kerkhof, E. Janssen, T. Tran Ngoc Minh, D. Iglesias van Montfort, C. Jamieson, I. Jordens, M. M. Maurice

This study shows RNF43 and ZNRF3 differentially regulate endocytosis of specific Frizzled family members through their transmembrane domains, linking these differences to cancer mutation patterns.

bioRxiv · Nov 23, 2023 · PreprintCell Biology

RNF43 truncating mutations mediate a tumour suppressor-to-oncogene switch to drive niche-independent self-renewal in cancer

M. Spit, N. Fenderico, I. Jordens, T. Radaszkiewicz, R. G. H. Lindeboom, J. M. Bugter, L. Ootes, M. van Osch, E. Janssen, K. E. Boonekamp, K. Hanakova, D. Potesil, Z. Zdrahal, S. F. Boj, J. P. Medema, , M. M. Maurice

This study identifies RNF43 truncating mutations that switch from tumor suppressor to oncogene, enabling niche-independent self-renewal in cancer and resistance to anti-Wnt therapy.

bioRxiv · Sep 1, 2019Cancer Biology

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

S. Kumari, M. Mak, Y. Poh, M. Tohme, N. Watson, M. Melo, E. Janssen, M. Dustin, R. Geha, D. Irvine

This study identifies a mechanical mechanism involving cytoskeletal tension that sustains T cell-APC synaptic contact symmetry and stability.

bioRxiv · May 4, 2019Cell Biology