I. Jungreis

This study identifies ORF3c as a SARS-CoV-2 protein that localizes to mitochondria and inhibits IFN-β production without affecting NF-κB or JAK-STAT signaling.

This study shows SARS-CoV-2 N-protein forms liquid-liquid phase separation with specific viral RNA sequences, which is temperature-sensitive and can be modulated by small molecules, offering potential for antiviral drug development.

The paper identifies thousands of novel unannotated proteins in cancer that contribute to the MHC I immunopeptidome, expanding potential targets for immunotherapy.

The paper identifies arginine as a major contributor to codon usage bias across domains of life and shows that domain-specific codon bias signatures can classify sequences into their domain with high accuracy.