Author

I. Nykonchuk

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Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1

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C. Bao· 1 shared D. Ermolenko· 1 shared D. Mathews· 1 shared H. Wakabayashi· 1 shared M. Zhu· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

C. Bao

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1 paper

Recent·Most cited

BiochemistrybioRxivAug 16, 2021

Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation

C. Bao, M. Zhu, I. Nykonchuk…·D. Ermolenko

The paper shows that specific length and structure, not high thermodynamic stability, of mRNA stem-loops cause ribosome pauses by inhibiting tRNA binding and slowing translocation.

DOI 10.1038/s41467-022-28600-5

E. colihuman

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