Author

C. Bao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

D. Ermolenko· 3 shared Z. Li· 2 shared A. A. Korostelev· 1 shared A. Das· 1 shared A. Sadagopan· 1 shared B. M. Wainger· 1 shared C. Gao· 1 shared C. J. Cardona· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBiochemistry

D. Ermolenko

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

PFS alleviates bone destruction in collagen-induced arthritis mice associated with macrophage polarization

G. Sun, C. Bao, X. Sun, Y. Liu

This study shows that PFS reduces bone destruction and shifts macrophage polarization from M1 to M2 in arthritis mice, suggesting its potential as an RA treatment.

bioRxiv · Jun 12, 2024 · PreprintImmunology

Addressing preferred orientation in single-particle cryo-EM through AI-generated auxiliary particles.

H. Zhang, D. Zheng, Q. Wu, N. Yan, Z. Shi, M. Hu, C. Bao

This paper introduces cryoPROS, an AI method to address preferred orientation in cryo-EM, improving resolution without special experimental techniques.

bioRxiv · Sep 26, 2023 · PreprintBiophysics

A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma

M. Achom, A. Sadagopan, C. Bao, F. McBride, Q. Xu, P. Konda, R. W. Tourdot, J. Li, M. Nakhoul, D. Gallant, U. A. Ahmed, J. O'Toole, D. Freeman, G.-S. M. Lee, J. Hecht, , S. R. Viswanathan

This study identifies a genetic basis for cancer sex differences in Xp11 translocation renal cell carcinoma by showing a 2:1 female:male ratio in TFE3 fusions involving the inactive X chromosome.

bioRxiv · Aug 4, 2023 · PreprintCancer Biology

Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes

A. Das, C. Bao, D. Ermolenko

The paper uses two FRET assays to study intersubunit rotation in bacterial ribosomes, finding spontaneous rotation occurs without EF-G and GTP hydrolysis.

bioRxiv · May 9, 2023Biochemistry

Highly synchronized cortical circuit dynamics mediate spontaneous pain

W. Ding, L. Fischer, Q. Chen, Z. Li, L. Yang, Z. You, K. Hu, X. Wu, X. Zhou, W. Chao, P. Hu, T. M. Dagnew, D. DuBreuil, S. Wang, S. Xia, , S. Shen

This study shows that spontaneous pain induces synchronized neural dynamics in the primary somatosensory cortex, and reversing this synchronization alleviates pain.

bioRxiv · Oct 4, 2022 · PreprintNeuroscience

Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation

C. Bao, M. Zhu, I. Nykonchuk, H. Wakabayashi, D. Mathews, D. Ermolenko

The paper shows that specific length and structure, not high thermodynamic stability, of mRNA stem-loops cause ribosome pauses by inhibiting tRNA binding and slowing translocation.

bioRxiv · Aug 16, 2021Biochemistry

mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding

C. Bao, S. Loerch, C. Ling, A. A. Korostelev, N. Grigorieff, D. Ermolenko

The paper investigates how mRNA stem-loops impede ribosome movement by hindering A-site tRNA binding and rotation during translation elongation.

bioRxiv · Feb 5, 2020Biochemistry

Susceptibility of Spotted Doves (Streptopelia chinensis) to Experimental Infection with the SFTS Phlebovirus

Z. Li, C. Bao, J. Hu, C. Gao, N. Zhang, X. Huo, C. J. Cardona, Z. Xing

This study shows that spotted doves can be infected with SFTSV, with severity depending on viral strain and dose, and suggests they may play a role in virus transmission.

bioRxiv · Nov 8, 2018Microbiology