Author

I. Shats

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. Liu· 2 shared X. Li· 2 shared A. V. Kabanov· 1 shared C. Lim· 1 shared E. Lee· 1 shared J. G. Williams· 1 shared J. Locasale· 1 shared J. W. Locasale· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

J. Liu

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Author profile →

2 papers

Recent·Most cited

Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

M. Ji, X. Xu, Q. Xu, X. Xu, M. A. Azcarate-Peril, X. Wu, J. Liu, J. W. Locasale, J.-L. Li, I. Shats, X. Li

This study shows that dietary methionine restriction worsens cancer growth and reduces anti-tumor immunity via gut microbiota and immune suppression in immunocompetent mice.

bioRxiv · Aug 27, 2021 · PreprintCancer Biology

Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway

I. Shats, J. Liu, J. G. Williams, L. J. Deterding, C. Lim, E. Lee, W. Fan, M. Sokolsky, A. V. Kabanov, J. Locasale, X. Li

This paper shows bacteria enhance mammalian NAD metabolism by using a deamidated biosynthesis pathway, contributing to drug resistance and improving NAD-boosting efficiency.

bioRxiv · Dec 7, 2018Biochemistry