Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism
I. Soaita, E. Megill, D. Kantner, A. Chatoff, Z. Arany, N. W. Snyder, K. E. Wellen, S. W. Trefely
This study shows that dynamic protein deacetylation in Acly-/- MEFs contributes carbons to acetyl-CoA but only transiently supplies about 9% of cellular acetyl-CoA.
bioRxiv · Dec 28, 2022Biochemistry