Cancer BiologybioRxivPreprint
The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin.
C. Stok, N. van den Tempel, M. Everts…·M. van Vugt
The paper identifies C1orf112 as a synthetic lethal partner of PICH, showing it stabilizes FIGNL1 and regulates RAD51 retention on chromatin, impacting genome maintenance.
DOI 10.1101/2022.10.07.511242