MicrobiologybioRxiv
Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2
N. P. Azouz, A. M. Klingler, V. Callahan…·M. E. Rothenberg
This study identifies alpha 1 antitrypsin (A1AT) as a TMPRSS2 inhibitor that limits SARS-CoV-2 dissemination by inhibiting extracellular proteases involved in viral entry.
DOI 10.20411/pai.v6i1.408