Cancer BiologybioRxiv
A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
J. L. Gillis, J. A. Hinneh, N. K. Ryan…·L. M. Butler
This study identifies a feedback loop between the androgen receptor and 6PGD that drives prostate cancer growth and shows that targeting both improves therapeutic efficacy.
DOI 10.7554/elife.62592