ImmunologybioRxiv
CRISPR-based functional genomics in human dendritic cells
M. Jost, A. N. Jacobson, J. A. Hussmann…·J. S. Weissman
This study develops a CRISPR/Cas9 method for human dendritic cells, enabling efficient gene knockouts and revealing mechanisms of immune response tuning to microbiome lipopolysaccharides.
DOI 10.7554/elife.65856