Vitamin D and the ability to produce 1,25(OH)2D are critical for protection from viral infection of the lungs.
J. Arora, D. R. Patel, M. J. Nicol, C. J. Field, K. H. Restori, J. Wang, N. E. Froelich, B. Katkere, J. A. Terwilliger, V. Weaver, E. Luley, K. Kelly, G. S. Kirimanjeswara, T. C. Sutton, M. T.-A. Cantorna
This study shows that vitamin D deficiency worsens lung inflammation during H1N1 and SARS-CoV-2 infections, while sufficient vitamin D reduces inflammation, though not viral replication.
bioRxiv · Jun 29, 2022Immunology