Author

J. Ault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Shaw· 1 shared A. Waddell· 1 shared E. Krysztofinska· 1 shared F. Sobott· 1 shared H. Ojha· 1 shared I. Urrutia· 1 shared J. C. Fitzgerald· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Kumar

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2 papers

Recent·Most cited

Mapping of a N-terminal α-helix domain required for human PINK1 stabilisation, Serine228 autophosphorylation and activation in cells

P. Kakade, H. Ojha, O. Raimi, A. Shaw, A. Waddell, J. Ault, S. Burel, K. Brockmann, A. Kumar, M. Ahanger, E. Krysztofinska, T. Macartney, R. Bayliss, J. C. Fitzgerald, M. Muqit

This study identifies an N-terminal α-helix domain in PINK1 critical for its stabilization, autophosphorylation, and activation, linking mutations in this region to Parkinson's disease.

bioRxiv · Sep 6, 2021Biochemistry

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.

I. Urrutia, J. Ault, F. Sobott, N. Savery, M. S. Dillingham

This study identifies a helicase interaction motif in the PcrA-RNAP complex and shows PcrA's role in suppressing R-loops by resolving transcription-replication conflicts.

bioRxiv · Mar 15, 2021Biochemistry